Velscot tablet 400mg / 100mg

About Velscot tablet 400mg / 100mg

Velscot tablet 400mg / 100mg Uses

• Treatment of chronic Hepatitis C infection in adults
• Used across multiple Hepatitis C virus genotypes
• Part of a complete antiviral course, with or without ribavirin as advised
• Used in people with or without liver cirrhosis under specialist care

Velscot tablet 400mg / 100mg Benefits

• High cure rates achieved in most people completing the full course
• Single daily tablet combining two antiviral mechanisms
• Effective across nearly all Hepatitis C genotypes common in Pakistan
• Shorter treatment duration compared to older Hepatitis C therapies

What Experts Say

Sofosbuvir and Velpatasvir target two different proteins the Hepatitis C virus needs to multiply. Sofosbuvir blocks the NS5B polymerase enzyme, while Velpatasvir blocks the NS5A protein, working together to stop the virus from replicating.

This combination is considered pangenotypic, meaning it works against nearly all strains of Hepatitis C found in Pakistan, which removes the need for genotype testing before starting treatment in most cases.

Treatment usually lasts twelve weeks, and doctors monitor viral load through blood tests during and after therapy to confirm the infection has cleared. People with advanced liver disease may need a longer course or closer monitoring.

Drug Class

• Direct acting antiviral combination
• NS5B polymerase and NS5A inhibitor
• Hepatitis C treatment regimen

Velscot tablet 400mg / 100mg formula

• Sofosbuvir 400mg
• Velpatasvir 100mg

Available forms

• Tablet

How to use Velscot tablet 400mg / 100mg?

• Take one tablet daily, with or without food, at the same time each day
• Complete the full prescribed course, usually twelve weeks
• Do not stop treatment early even if you feel well
• Attend all follow up blood tests as scheduled by your doctor
• Avoid alcohol during the course of treatment

Drug Interactions

• Amiodarone: Combining can cause severe slowing of the heart rate.
• Acid Reducing Medicines: Antacids, H2 blockers, and proton pump inhibitors can lower absorption if timing is not managed properly.
• Certain Seizure Medicines: Can reduce the effectiveness of this antiviral combination.
• Rifampin: Significantly lowers drug levels and should generally be avoided.

Risks and warnings

• Hepatitis B Reactivation: Can reactivate hepatitis B in people previously infected, screening beforehand is recommended.
• Liver Function: Requires monitoring in people with advanced liver disease.
• Pregnancy: Safety in pregnancy is not fully established, discuss with your doctor.
• Amiodarone Use: Combining with this heart medicine can cause dangerously slow heart rate.
• Specialist Supervision: Should only be used under the guidance of a doctor experienced in Hepatitis C treatment.

Velscot tablet 400mg / 100mg Side Effects

• Headache
• Fatigue
• Nausea
• Diarrhea
• Trouble sleeping
• Irritability
• Rare slow heart rate with certain heart medicines
• Rare hepatitis B reactivation

Storage Conditions

• Store below 30 degrees Celsius in a dry place
• Keep the tablets in their original packaging
• Protect from moisture and direct heat
• Keep out of reach of children